Publication

Combination of cell-penetrating peptides with nanoparticles for therapeutic application: A review

Bibliographic Details
Summary:Cell-penetrating peptides (CPPs), also known as protein translocation domains, membrane translocating sequences or Trojan peptides, are small molecules of 6 to 30 amino acid residues capable of penetrating biological barriers and cellular membranes. Furthermore, CPP have become an alternative strategy to overcome some of the current drug limitations and combat resistant strains since CPPs are capable of delivering different therapeutic molecules against a wide range of diseases. In this review, we address the recent conjugation of CPPs with nanoparticles, which constitutes a new class of delivery vectors with high pharmaceutical potential in a variety of diseases.
Subject:Therapeutic molecule Membrane translocation Delivery systems Cell-penetrating peptides Nanoparticles
Country:Portugal
Document type:journal article
Access type:Open
Associated institution:Repositório Aberto da Universidade do Porto
Language:English
Origin:Repositório Aberto da Universidade do Porto

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