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Perfil epidemiológico dos isolamentos dos microrganismos ‘Problema’

Bibliographic Details
Summary:Introduction: Infections are a major problem and the presence of drug-resistant microorganisms has significant clinical and economic impact. The present study aims to evaluate the epidemiological profile of “problem” microorganisms isolated in a hospital in the north of Portugal.Material and Methods: All isolated microorganisms were analyzed, between January 2014 and June 2015. Data obtained was then processed using statistical software.Results: We analyzed 8146 microbiological isolations and found a prevalence of 23% of ‘problem’ microorganisms (in descending order of frequency: Enterococcus, Pseudomonas, Staphylococcus aureus e Streptococcus pneumonia), 57.55% of which isolated in male patients. The most frequent mechanism of drug resistance for the overall sample was the production of extended-spectrum beta-lactamase, and resistance to oxacillin for ‘problem’ microorganisms.Discussion: In this sample, we observed a much higher prevalence of ‘problem’ microorganisms than that reported in other countries, which shows the need of improvement of surveillance mechanisms and treatment of these cases. Microorganisms that showed higher resistance were Staphylococcus aureus (resistant to oxacillin) and Enterococcus (resistant to vancomycin). Those were isolated in patients with a higher mean age compared to non-resistant microorganisms. Most of these microorganisms were isolated in hospitalized patients or intermediate and intensive care units, what relates them with healthcare associated infections.Conclusion: The prevalence of infection by ‘problem’ microorganisms during the studied period was 23%. The detection and control of the spread of these microorganisms are paramount due to its impact on health costs, morbidity and survival of patients.
Authors:Escola Nacional de Saúde Pública (ENSP); Centro de Investigação em Saúde Pública (CISP/PHRC)
Subject:Portugal Drug Resistance, Microbial Medicine(all) Infecção/epidemiologia; Portugal; Resistência Microbiana a Medicamentos Infection/epidemiology Drug Resistance, Microbial; Infection/epidemiology; Portugal
Year:2019
Country:Portugal
Document type:journal article
Identifiers:ID: PURE: 14858075
Access type:Open
Associated institution:Acta Médica Portuguesa, Repositório Institucional da UNL, RUN
Funded project code:PURE: 14858075
Language:Portuguese
Origin:Acta Médica Portuguesa